A Phase III trial has demonstrated that patients with advanced Stage III/IV classic Hodgkin lymphoma who underwent initial treatment with nivolumab, a PD-1 checkpoint inhibitor, and AVD chemotherapy (N-AVD) had a significantly lower risk of their cancer getting worse than patients treated with brentuximab vedotin, a monoclonal antibody, and AVD (BV-AVD) a year after starting treatment.

The number of cancer survivors with self-reported functional limitations throughout the United States has more than doubled over the past 2 decades, according to data published in JAMA Oncology.

Childhood cancer survivors have increased rates of undergoing late, major surgical procedures 5 or more years after diagnosis, according to data from the Childhood Cancer Survivor Study.

The first study to demonstrate an association between therapeutic radiation dose to the large bowel and colorectal cancer.

In a new study, the majority of individuals treated as children for Hodgkin lymphoma who are now in their 30s, showed signs of being an average of 7.7 years older biologically than their peers and placing them at risk for cognitive problems.

While the treatment of various cancers using radiation therapy for conditions including Hodgkin’s disease is regarded as a “medical miracle”, patients are often unaware that radiation can negatively impact organs including the heart, the lungs and the esophagus. Specific to the heart, there is a strong association among radiation therapy and heart valve disease, coronary artery disorders, ascending aorta defects and pericardium issues.

This article describes the results of a study from the University of California San Francisco. It highlights one of the topics Dr. Micheal Stubblefield mentioned in his presentation at our conference. It comes from a paper that was published in the British Medical Journal Supportive and Palliative Care, July 2022. First author Steven W. Cheung, MD notes the marked incidence of hearing loss and tinnitus in survivors, owing to chemotherapy drugs that contained platinum as well as those that contained taxanes.

Death due to a second primary cancer occurred nearly twice as often among adolescent and young adult cancer survivors compared with the general population, according to study results published in Journal of the National Cancer Institute.

Over the past several years, researchers have developed AI tools that have the potential to make cancer imaging faster, more accurate, and even more informative. And that’s generated a lot of excitement.

In this issue of the Journal, de Vries and colleagues examine the cause-specific late mortality among a multi-center Dutch cohort of Hodgkin lymphoma survivors.