This article describes the results of recent study published in the JAMA Internal Medicine. It explores a fairly common side effect of some cancer treaments, “chemotherapy-induced peripheral neuropathy,” or CIPN. More than just an annoying condition, CIPN can have a significant effect on the quality of life for survivors. The study presented here offers some exciting news about possible treatments for this condition.
Many women who are long-term Hodgkin’s survivors experience early menopause as a result of their radiation and chemotherapy treatments, especially if they received them at a young age. As we are already at risk for breast cancer due to the same treatments, it is important to be aware of any additional risk factors.
Interesting study from the St. Jude Lifetime Cohort (SJLIFE), and originally published int the Journal of Clinical Oncology. The results may not be surprising, but it does appear that a plant-based diet has even more significance for childhood cancer survivors when it comes to premature aging and other health factors. (Note: the term “childhood cancer survivors” may include young adults in their 20’s).
Here is a brief summation of a research study published by the JCO Oncology of Practice (May 24, 2024) that appeared in the Cancer Therapy Advisor. In short, it describes the decline in follow-up care with primary care providers after five years of completing treatment.
A new first-line chemotherapy regimen of prednisone, vinblastine, doxorubicin, and bendamustine (PVAB) yields a high complete metabolic response (CMR) rate with acceptable toxicity in older patients with classical Hodgkin lymphoma (cHL), according to research published in Blood.
This article describes research done by the Childhood Cancer Survivor Study of St. Jude Children’s Research Hospital and CARDIA, which stands for “Coronary Artery Risk Development in Young Adults.” These two organizations combined their data bases to create an in-depth study of the specific risks for childhood cancer survivors. The results are concerning, and they underline the need for early and frequent observation post treatment.
This article in HemOnc Today describes a recent study that evaluated the use of specific biomarkers, namely global longitudinal strain (GLS) and N-terminal-pro-B-type natriuretic peptide (NT-proBNP) to identify childhood cancer survivors who may be at risk for cardiomyopathy. The study was done through the St. Jude Lifetime Cohort study.
This research paper takes a look at the risk of breast cancer from doxorubicin exposure in female survivors of Hodgkin lymphoma who are between the ages of 15-50 years of age and five years post treatment. The period of treatment was between 1975 and 2008. The study was first presented in 2021 at the ASCO Annual Meeting.
Of note is that the authors found an increased risk of breast cancer in this cohort independent of whether or not radiation was also a part of the treatment protocol.
When thinking about cancer research, many people think of studies focused on evaluating new or better ways to treat the cancer itself. What may not come to mind is a type of research known as “survivorship research.”